Setting up JDBC Database Connection Pool in Spring framework is easy for any Java application, just matter of changing a few configurations in the spring configuration file. If you are writing core java application and not running on any web or application server like Tomcat or Weblogic, Managing Database connection pool using Apache Commons DBCP and Commons Pool along-with Spring framework is a nice choice but if you have the luxury of having web server and managed J2EE Container, consider using Connection pool managed by J2EE server those are a better option in terms of maintenance, flexibility and also help to prevent java.lang.OutofMemroyError: PermGen Space in tomcat by avoiding loading of JDBC driver in web-app class-loader.